Common Diseases & Disorders Codexery

Color blindness

Color blindness is a decreased ability to perceive color differences.

Color blindness

Color blindness, or color vision deficiency (CVD), is the decreased ability to see color, differences in color, or distinguish shades of color. The severity ranges from mostly unnoticeable to full absence of color perception. It is usually a sex-linked inherited problem or variation in the functionality of one or more of the three classes of cone cells in the retina, which mediate color vision.

most common form
congenital red–green color blindness (protan and deutan types)
prevalence in males
up to 1 in 12 (8%)
genetic cause
opsin genes on the X chromosome
other genetic forms
congenital blue–yellow color blindness (tritan type), blue cone monochromacy, achromatopsia
acquired causes
physical or chemical damage to the eye, optic nerve, parts of the brain, medication toxicity, old age

Lore & Background

Color blindness is typically classified using the von Kries classifications, based on severity and affected cone. Total color blindness (monochromacy) is much less common than partial color blindness. Partial color blindness includes dichromacy and anomalous trichromacy, often clinically defined as mild, moderate, or strong. Monochromacy includes rod monochromacy (complete achromatopsia) and blue cone monochromacy, the latter caused by lack of functionality of L and M cones and linked to the X chromosome. Dichromats can match any color with a mixture of just two primary colors; types include protanopia, deuteranopia, and tritanopia. Anomalous trichromacy is the mildest type, with severity ranging from almost dichromacy to almost normal trichromacy.

Reader's Guide

Color blindness has significant implications for daily life and career eligibility. Depending on jurisdiction, color blind people are ineligible for careers such as aircraft pilots, train drivers, police officers, firefighters, and members of the armed forces. Diagnosis is usually done with a color vision test like the Ishihara test. There is no cure for most causes, though research into gene therapy for severe conditions is ongoing. Minor forms do not significantly affect daily life, and individuals develop adaptations and coping mechanisms. Color blind glasses may help with some color tasks but do not grant normal color vision. Mobile apps can use a device's camera to identify colors. The effect on artistic ability is controversial, but a number of famous artists are believed to have been color blind. The condition is more prevalent in males due to X-chromosome-linked opsin genes.

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